How to Open ChemSketch files (*.sk2) with ChemDraw application.
Currently *.sk2 file format is not supported with ChemDraw.
As a workaround if you are able to convert your ChemSketch files *.sk2 with any of the supported file format then you can open with ChemDraw.
You can save the ChemSketch document as CS ChemDraw (*.cdx) and open with the ChemDraw application. Alternatively you can copy/paste the selected structures from ChemSketch to ChemDraw directly.