The ChemDraw for Excel Add-in is not loaded and when added manually the buttons do not work.

The ChemDraw for Excel Add-in is not loaded and when added manually the buttons do not work.

Recent updates from Microsoft seem to have affected several versions of MS Office, conflicting with the ChemDraw Add-in. In order to correct this problem you must perform a clean installation of both, MS Office and ChemDraw / ChemOfice.

First uninstall ChemDraw or ChemOffice. Then follow the instructions on this website to remove MS Office:

https://support.office.com/en-us/article/Manually-uninstall-Office-4e2904ea-25c8-4544-99ee-17696bb3027b?ui=en-US&rs=en-US&ad=US#OfficeVersion=2016

Finally reinstall ChemDraw and test it.