Signals ChemDraw 25.5 Release

Revvity Signals is delighted to announce the release of ChemDraw v25.5 for ChemDraw Prime, Professional & Signals ChemDraw. This minor release of ChemDraw Desktop focuses on property calculations, HELM handling, and extended Python support for ChemScript. We’ve also addressed a number of bugs to ensure a smoother experience.

What's New in ChemDraw

ChemDraw Desktop v25.5 Updates

Available in all offerings: ChemDraw Prime, ChemDraw Professional & Signals ChemDraw

Properties Calculations

• LogP and Molar Refractivity (MR) calculations are now powered by RDKit
• Property calculations have also been optimized for efficiency

 Available in ChemDraw Professional & Signals ChemDraw

Advanced Biopolymer (HELM) Improvements

• Improved biopolymer clean-up of complementary strands
• Sequence selection behavior has been improved to use double and triple click behaviors
• 'Copy As HELM (natural analog)' updated to 'Copy as FASTA' for clarity

Python Support

• ChemScript now supports Python versions 3.13.x, 3.10.x, and 3.9.x

ChemDraw+

Exclusive to Signals ChemDraw offering and released continuously throughout the year in the Signals Platform, ChemDraw+ is a cloud-native version of ChemDraw allowing you to create, manage and curate your drawings using a web browser.

Chemistry Improvements

• Enhanced selection behavior for atoms, bonds and structures for visual clarity
• Attach Data can now be added as chemically significant
• Name to Structure capability expanded to use ChemACX
• Periodic table tool now available, with the ability to create atom lists
• Chemical objects can now be copied as ‘MolV3000 (Expanded)’
• Chemical Object colors can now be changed
• Ring Fill coloring can now be applied
• Mass Fragmentation tool now available
• Alignment tools now available

Advanced Biopolymer (HELM) Improvements

• Drawing of individual RNA/DNA monomers when editing biopolymers is now possible
• Hydrogen bonded fragments are now treated as a single structure
• Monomers can now be selected in bulk for replacement
• Monomers can now be searched for, found and replaced when editing biopolymers
• Copy As HELM (natural analog)' updated to 'Copy as FASTA'

Expanded Application Capabilities

• Drawing settings are now customizable providing enhanced control to create drawings tailored to specific formatting needs
• Basic chemical properties are available in the Analysis panel and can be pasted onto the canvas
• “Created by” filter now available on the Dashboard
• Drawings can be exported as molfiles and sdfiles (v3000)

 For more information on any of the new features highlighted with this release, please visit the Signals ChemDraw What’s New website, which provides details of each ChemDraw release.

Product Compatibility

ChemDraw v25.5 is qualified against the following: 

• Windows 10 (64-bit) and Windows 11 (64-bit)
• Microsoft Office 2021, Microsoft Office 2024, and Microsoft Office 365
• macOS 15.7.2 (Sequoia) and 126.0.1 (Tahoe) – (for ChemDraw only)
• Adobe Acrobat DC

ChemDraw Prime and Professional are available through the Revvity Signals Download Center. If you do not have access to the Download Center, contact Revvity Signals Support to assist you with sign-up.

Signals ChemDraw is available through the Signals Research Platform with an active license. Please contact your Account Manager if you are interested in purchasing.

https://revvitysignals.com/signals-chemdraw-whats-new