ChemDraw: Does changing my IP address affect my ChemDraw activation

Does changing my IP address affect my ChemDraw activation?

Changing the IP address will not remove the license information.  
Sometimes a change on your network configuration (change from wired to wireless, VPN connection or use of a docking station) can make the host ID change, causing the software to prompt for activation again.

If this happens, you can set your fixed host ID by following the instructions here