One reason for this error may be that your IT team is blocking user level native messaging hosts.
Solution:
You would need to do an Admin install (“install for all users”) of ChemDraw Web Clipboard.exe. Please find the screenshot below:
Steps to enable extended copy/paste functionality of ChemDraw is detailed in the KB Article: https://support.revvitysignals.com/hc/en-us/articles/4408233094036-How-do-I-enable-extended-copy-paste-functionality-for-ChemDraw-Cloud-