Modify the ChemDraw Preferences from the Signals Configuration

For Administrators only. 

1️⃣ Signals Configuration ➡ select [Chemistry Settings]
2️⃣ Chemistry Settings pane ➡ select ChemDraw Preferences
3️⃣ ChemDraw Preferences section ➡ Normalize Aromatic Display ➡ select [“option to normalize aromatic ring”]
4️⃣ ChemDraw Preferences section ➡ Mol: Ignore Top Level Chiral Flag ➡ select (when this setting is enabled, the top-level chiral flag will be ignored for the mol file)
5️⃣ ChemDraw Preferences section ➡ select [Save Settings]

Supporting Knowledge 

Notes:

• Administrators can define that chemical structures containing delocalized rings that have been imported from mol or SMILES format can be converted from aromatic to alternating single- and double-bond representation, or vice versa.
  • This setting will be applied to structures pasted into a ChemDraw document that is in SMILES or mol format, or when structures are imported via SDfile. The setting will not apply to imported .cdx or .cdxml files.

Normalize Aromatic Display area:

• No change: delocalized rings will be represented as specified in the mol or SMILES format.
• Alternating Double/Single Bonds: all pasted rings will be converted to alternating single- and double-bond representation.
• Aromatic Circles: all pasted rings will be represented with aromatic circles.

Mol: Ignore Top Level Chiral Flag area:

If the checkbox option "When this setting is ticked, the top-level chiral flag will be ignored for the mol file" is enabled, then the top-level chiral flag is not retained. To display the top-level chiral flag for the end user, deselect the checkbox.