Why do I get errors during substance management actions for roles other than INV_ADMIN and INV_REGISTRAR?

Why do I get errors during substance management actions for roles other than INV_ADMIN and INV_REGISTRAR?

There are missing grants to the CS_SECURITY user that cause missing grants to roles that are assigned the INV_MANAGE_SUBSTANCES privilege.  To fix this issues:

1. Connect as:
   cheminvdb2/oracle
2. Execute the following grants:

       GRANT EXECUTE ON GETCOMPOUNDID TO CS_SECURITY WITH GRANT
       OPTION;
       GRANT EXECUTE ON ISDUPLICATECOMPOUND TO CS_SECURITY WITH
       GRANT OPTION;
       GRANT EXECUTE ON SUBSTANCENAMEEXISTS TO CS_SECURITY WITH
       GRANT OPTION;
     

3. Use the Manage Roles Interface to reassign the INV_MANAGE_SUBSTANCES privilege to all Roles that require it.