Scripts are not staying trusted after being saved to the library.

For scripts to be trusted, users who are allowed, need to have both the Author Scripts licence and be in the Script Author group.

Solution:

The Script author license can be found in the TIBCO Spotfire Extensions -> Author Scripts.

You are best to tick this inside your Script Author group (it is not ticked by default), then all you have to do is put your required users inside of this group.  You then have both requirements in one solution.