ChemDraw: During installation, which option do I choose for 32-bit or 64-bit ChemScript installation?

The ChemOffice installer contains both 32-bit and 64-bit versions of Python to match the "bit-ness" of ChemScript.

Select ChemScript 32-bit if you are running 32-bit versions of Microsoft Office and Office 365.

Likewise, select ChemScript 64-bit if you are running 64-bit versions of Microsoft Office and Office 365.

We do not recommend installing ChemScript 64-bit against MS Office 32-bit, or ChemScript 32-bit against MS Office 64-bit.