ChemDraw for Excel: Disabled macros error when opening ChemDraw for excel file

I see the 'Disabled macros error' when opening ChemDraw for excel file.

You can change macro settings in the Trust Center by following the steps here.

1. Click the File tab.
2. Click Options.
3. Click Trust Center, and then click Trust Center Settings.
4. In the Trust Center, click Macro Settings.
5. Make sure "Enable Excel 4.0 Macros..." is selected.  Select Enable VBA macros or Disable VBA macros with notification.