Version 26.0
Hardware Requirements
Memory (RAM)
• 64-bit OS: Minimum 2 GB, Recommended 3 GB
Processor
• Minimum 1.6 GHz or higher, Recommended 3.0 GHz or higher dual-core processor
Free Space Required on Hard Drive
• Minimum 1 GB - 4 GB (4 GB is for installing the full ChemOffice Professional version.) This is for installation only and does not include any creation/expansion of any databases.
• 10 GB recommended specification
Screen
• Resolution: 1024 x 768 or higher recommended specification
• Windows 11 (64 bit)
.Net Framework
• .NET Framework 4.8
Macintosh
Operating System
• macOS Sequoia (15.7.4)
• macOS Tahoe (26.4.1)
Microsoft Office (Professional, or Enterprise) for 32 bit only
The latest update used for testing is 16.106.3 (26030211).
• Office 365
• Microsoft Office 2021
• Microsoft Office 2024
Version 25.0
Hardware Requirements
Memory (RAM)
• 64-bit OS: Minimum 2 GB, Recommended 3 GB
Processor
• Minimum 1.6 GHz or higher, Recommended 3.0 GHz or higher dual-core processor
Free Space Required on Hard Drive
• Minimum 1 GB - 4 GB (4 GB is for installing the full ChemOffice Professional version.) This is for installation only and does not include any creation/expansion of any databases.
• 10 GB recommended specification
Screen
• Resolution: 1024 x 768 or higher recommended specification
• Windows 11 (64 bit)
.Net Framework
• .NET Framework 4.8
Macintosh
Operating System
• macOS Sonoma (14.7)
• macOS Sequoia (15.5)
Microsoft Office (Professional, or Enterprise) for 32 bit only
The latest update used for testing is 16.97 (2501114).
• Office 365
• Microsoft Office 2021
• Microsoft Office 2024
Version 23.0
Hardware Requirements
Memory (RAM)
• 64-bit OS: Minimum 2 GB, Recommended 3 GB
Processor
• Minimum 1.6 GHz or higher, Recommended 3.0 GHz or higher dual-core processor
Free Space Required on Hard Drive
• Minimum 1 GB - 4 GB (4 GB is for installing the full ChemOffice Professional version.) This is for installation only and does not include any creation/expansion of any databases.
• 10 GB recommended specification
Screen
• Resolution: 1024 x 768 or higher recommended specification
Windows
Operating System
• Windows 10 (64 bit)
• Windows 11 (64 bit)
Microsoft Office (Professional, or Enterprise)
Note: We test with the latest versions of MS Office available at the time, but that is no guarantee of full compatibility with future updates. The latest update used for testing is 2312 (Build 16.0.17216.20132).
• Microsoft Office 2019 (32-bit and 64-bit)
• Microsoft Office 2021 (32-bit and 64-bit)
• Office 365 (32-bit and 64-bit)
.Net Framework
• .NET Framework 4.8
Browser ActiveX controls
• Microsoft Edge in Internet Explorer (IE) mode
Macintosh
Operating System
• macOS Ventura (13.6)
• macOS Sonoma (14.2)
Microsoft Office (Professional, or Enterprise) for 32 bit only
The latest update used for testing is 16.81 (24011402).
• Microsoft Office 2019
• Microsoft Office 2021
• Office 365
Browser ActiveX controls
Not Applicable
Version 22.0
Hardware Requirements
Memory (RAM)
• 64 bit OS: 2 GB recommended specification
Processor
• Minimum 1.6 GHz or higher, Recommend 3.0 GHz or higher dual-core processor
Free Space Required on Hard Drive
• Minimum 300 MB - 1 GB (1 GB is for installing the full ChemOffice Professional version.) This is for installation only and does not include any creation/expansion of any databases.
• 10 GB recommended specification
Screen
• Resolution: 1024 x 768 or higher recommended specification
ChemDraw/ChemOffice for Windows
Operating System
• Windows 10 (64 bit)
• Windows 11 (64 bit)
Microsoft Office (Standard, Professional, or Enterprise)
Note: We test with the latest versions of MS Office available at the time, but that is no guarantee of full compatibility with future updates. The latest update used for testing is 2208 (Build 16.0.15601.20078).
• Microsoft Office 2019 (32-bit and 64-bit)
• Microsoft Office 2021 (32-bit and 64-bit)
• Office 365 (32-bit and 64-bit)
.Net Framework
• .Net Framework 4.8
Browser ActiveX controls
• Microsoft Edge in Internet Explorer (IE) mode
ChemDraw Prime / ChemDraw Professional for Macintosh
Operating System
• macOS Big Sur (11.6)
• macOS Monterey (12.5)
• macOS Ventura (13.0)
Microsoft Office (Standard, Professional, or Enterprise) for 32 bit only
The latest update used for testing is 16.64 (22081401).
• Microsoft Office 2019
• Microsoft Office 2021
• Office 365
Browser ActiveX controls
Not Applicable
Note: The ChemDraw & Chem3D Plugins are no longer part of any ChemOffice/ChemDraw package. The ChemDraw & Chem3D ActiveX controls are still included with Windows packages.
Version 21.0
Hardware Requirements
Memory (RAM)
• 32 bit OS: 1 GB recommended specification
• 64 bit OS: 2 GB recommended specification
Processor
• Minimum 1.6 GHz or higher, Recommend 3.0 GHz or higher dual-core processor
Free Space Required on Hard Drive
• Minimum 300 MB - 1 GB (1GB is for installing the full ChemOffice Professional version.) This is for installation only and does not include any creation/expansion of any databases.
• 10 GB recommended specification
Screen
• Resolution: 1024 x 768 or higher recommended specification
ChemDraw/ChemOffice for Windows
Operating System
• Windows 10 (64 bit)
• Windows 11 (64 bit)
Microsoft Office (Standard, Professional, or Enterprise)
Note: We test with the latest versions of MS Office available at the time, but that is no guarantee of full compatibility with future updates. The latest update used for testing is 2008 (13127.20408).
• Microsoft Office 2019 (32-bit and 64-bit)
• Microsoft Office 2021 (32-bit and 64-bit)
• Office 365 (32-bit and 64-bit)
.Net Framework
• .Net Framework 4.x
Browser ActiveX controls
• Microsoft Internet Explorer 11.x (32-bit and 64-bit)
ChemDraw Prime / ChemDraw Professional for Macintosh
Operating System
• macOS Big Sur (11.6)
• macOS Monterey (12.1)
Microsoft Office (Standard, Professional, or Enterprise) for 32 bit only
The latest update used for testing is 16.41 (20091302).
• Microsoft Office 2019
• Microsoft Office 2021
• Office 365
Browser ActiveX controls
Not Applicable
Note: The ChemDraw & Chem3D Plugins are no longer part of any ChemOffice/ChemDraw package. The ChemDraw & Chem3D ActiveX controls are still included with Windows packages.
Version 20.0
Hardware Requirements
Memory (RAM)
• 32 bit OS: 1 GB recommended specification
• 64 bit OS: 2 GB recommended specification
Processor
• Minimum 1.6 GHz or higher, Recommend 3.0 GHz or higher dual-core processor
Free Space Required on Hard Drive
• Minimum 300 MB - 1 GB (1GB is for installing the full ChemOffice Professional version.) This is for installation only and does not include any creation/expansion of any databases.
• 10 GB recommended specification
Screen
• Resolution: 1024 x 768 or higher recommended specification
ChemDraw/ChemOffice for Windows
Operating System
• Windows 7 Professional and Ultimate (32 bit)
• Windows 7 Professional and Ultimate (64 bit)
• Windows 8.1 (64 bit)
• Windows 10 (64 bit)
Microsoft Office (Standard, Professional, or Enterprise)
Note: We test with the latest versions of MS Office available at the time, but that is no guarantee of full compatibility with future updates. The latest update used for testing is 2008 (13127.20408).
• Microsoft Office 2016 (32-bit and 64-bit)
• Microsoft Office 2019 (32-bit and 64-bit)
• Office 365
.Net Framework
• .Net Framework 4.x
Browser ActiveX controls
• Microsoft Internet Explorer 11.x (32-bit and 64-bit)
ChemDraw Prime / ChemDraw Professional for Macintosh
Operating System
• macOS Mojave (10.14)
• macOS Catalina (10.15)
• macOS Big Sur(11)
Microsoft Office (Standard, Professional, or Enterprise) for 32 bit only
The latest update used for testing is 16.41 (20091302).
• Microsoft Office 2016
• Microsoft Office 2019
• Office 365
Browser ActiveX controls
Not Applicable
Note: The ChemDraw & Chem3D Plugins are no longer part of any ChemOffice/ChemDraw package. The ChemDraw & Chem3D ActiveX controls are still included with Windows packages.
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