Spectrus: NMR – Using line broadening and apodization to improve spectral appearance

Description
Raw NMR FID data can be processed with different apodization (window) functions and line broadening values. Proper use of these settings can improve signal‑to‑noise ratio and peak appearance without excessively degrading resolution.

Solution

1. Load the NMR dataset (FID) in Spectrus.
2. Open the Processing or Apodization settings.
3. Choose an apodization function (e.g., exponential, Gaussian, or mixed).
4. Start with a small line broadening value (e.g., 0.2–0.3 Hz for 1H) and apply the transform.
5. Inspect the spectrum:
   • If noise is still high, incrementally increase line broadening.
   • Avoid large values that visibly widen or merge close peaks.
6. Once a good compromise is found between S/N and resolution, apply the same settings to related spectra in the series for consistency.
7. Proceed with phase and baseline correction, then peak picking and integration.