Irina Oshchepkova
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Articles
Recent activity by Irina Oshchepkova-
AutoChrom: Using software in a validated environment (general guidance)
DescriptionIn environments where instruments and chromatography data systems are fully validated, AutoChrom is often used on separate, non‑instrument PCs. IT or validation groups may perform their ...
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LC Simulator: Modes Manager: “Approximation” vs. “Spline” and required run count
DescriptionIn Modes Manager (for example, Gradient Optimization), some models use polynomial approximation (e.g., quadratic: ln k' = a + bx + cx²), while others use spline models. The “Requires … r...
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LC Simulator: Meaning of “Flow Rate” fields and how t₀ is calculated
DescriptionIn LC Simulator there are two separate flow rate fields:“At a Flow Rate of” (in Column Parameters): flow rate used when the Observed t₀ and Observed Pressure values were measured.“Consta...
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AutoChrom: Supported CDS Configuration and Requirements
DescriptionUsers often need to know which Chromatography Data System (CDS) versions and configuration work with AutoChrom Online.For details, please refer to Automated (QbD) Method Development Soft...
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ChromGenius: Molecules with No Estimated tR Values
DescriptionWhen running Estimate Prediction Accuracy in ChromGenius, some molecules may appear in gray, with no estimated retention time (tR) values. This indicates that the software was unable to ...
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Spectrus: Column Selection, Column Comparison, and LC Method Transfer Assistant are missing from the Tools menu.
DescriptionQbD tools are not accessible from Tools menu in Spectrus ProcessorLC Method Transfer AssistantLC Columns ComparisonLC Columns SelectionAfter installation, users do not see these QbD tool...
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Empower Add-on: Interface Registration Issue
DescriptionWhen launching the Addon from the Application menu within Empower, the ‘Interface is not registered’ error appears. Registration of the required interfaces may have been disrupted, often...
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Spectrus: Cannot import Agilent 6000 and Bruker Compass data in *.D format
DescriptionThis article will teach you how to set up the required libraries and options to ensure the Agilent LCMS 6000 and Bruker CompassXtract import filters work properly.SolutionEnsure that .NE...
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Activation: Automatic activation fails behind corporate proxy or in offline network
DescriptionOnline (automatic) activation may fail on machines that are behind a strict corporate proxy or do not have direct Internet access. In these cases, users typically see a timeout or a gene...
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Activation: ‘Cannot unpack response’ message during manual activation
DescriptionWhen attempting manual activation, the user receives a “cannot unpack response” error.SolutionA common issue is that Registration keys are mistakenly used to activate the software. These...