Katalyst: Upload of very large raw analytical data files fails or stalls

Description

• Users attempt to upload very large instrument data sets (e.g., multi‑GB LC/MS or LC‑UV runs).
• Uploads:
  • Stall partway,
  • Fail with timeouts, or
  • Complete but the data never appears in the Analysis Workspace.
• Smaller files from the same instrument upload without issues.

Solution

• Check infrastructure limits:
  • Web server/proxy maximum request size.
  • Upload timeout limits.
  • Disk space on the receiving share or server.
• Adjust settings where possible:
  • Increase max upload size and timeouts in the web server / reverse proxy hosting Katalyst.
  • Ensure the Katalyst scan/ingest locations have sufficient free disk space.
• Best practices:
  • Where possible, split excessively large acquisition runs into smaller, logically separate data sets.
  • Avoid bundling unrelated runs into a single massive file.